A COBALT OXIDE CARBON NANOTUBE COMPOSITE FOR DOPAMINE DETECTION

Abstract

Dopamine (DA) is a catecholamine and performs as a neurotransmitter in the human body. Dopamine plays an important role in the process of many biological networks. Research showed that unusual amounts of DA can cause several neurological diseases such as Parkinson’s disease, schizophrenia, and other mental disorder. Cobalt oxide (CoO) particles were tethered to carboxylic-acid-functionalized multi-walled carbon nanotubes (COOH-MWNT) using sonication. The resulting composite (CoO/COOH-MWNT) was applied to glassy carbon electrodes for detecting DA within the 0.5-5 µM range and 10-100 µM range. Current versus concentration was measured using cyclic voltammetry. Different parameters such as loading, pH and sonication times (0 to 60 min) were varied to optimize current response. Good selectivity was found against uric acid and ascorbic acid. The (CoO/COOH-MWNT) composite was characterized by attenuated total reflection infrared spectroscopy (ATR-IR), Raman spectroscopy, Transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS).