DEEP EUTECTIC SOLVENTS (DES) AS CATALYST AND SOLVENT FOR KNOEVENAGEL CONDENSATION REACTIONS

dc.contributor.advisor Handy, Scott
dc.contributor.author Almuzaini, Hanan
dc.contributor.committeemember Ding, Keying
dc.contributor.committeemember Bicker, Kevin
dc.contributor.department Chemistry en_US
dc.date.accessioned 2015-12-18T19:11:58Z
dc.date.available 2015-12-18T19:11:58Z
dc.date.issued 2015-11-10
dc.description.abstract ABSTRACT
dc.description.abstract The Knoevenagel condensation reaction is one of the most important condensation reactions that can be used in different areas such as cosmetics, perfumes, pharmaceuticals, calcium antagonists and polymers [1]. Usually, it is carried out in organic solvents. Bases such as ammonia, primary or secondary amines, and their salts can catalyze a Knoevenagel reaction [2-3]. Several heterogeneous catalysts such as aluminum oxide [4], alkali-containing MCM-41 [5], and zeolites [6] can also be used to catalyze this reaction. Recently, with the development of the green chemistry concept, which seeks to reduce negative environmental impact [8], the Knoevenagel condensation reaction was rewritten under greener conditions. It was found that deep eutectic solvents (DES), a mixture of two or three cheap and safe solid components that are capable of associating with each other through hydrogen bond interactions [19], are a good option to catalyze this type of reaction. DES is inexpensive, safe, and easy to recycle. This type of reaction conditions gave a high yield under a smooth process in a short time [28]. By using a deep eutectic solvent (choline chloride/urea) as a catalyst and solvent, different factors that could affect the Knoevenagel condensation reaction, such as the effect of substituted groups in active methylene compounds on the yield of the products, can be studied.
dc.description.degree M.S.
dc.identifier.uri http://jewlscholar.mtsu.edu/handle/mtsu/4762
dc.publisher Middle Tennessee State University
dc.subject.umi Chemical engineering
dc.thesis.degreegrantor Middle Tennessee State University
dc.thesis.degreelevel Masters
dc.title DEEP EUTECTIC SOLVENTS (DES) AS CATALYST AND SOLVENT FOR KNOEVENAGEL CONDENSATION REACTIONS
dc.type Thesis
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Almuzaini_mtsu_0170N_10513.pdf
Size:
12.29 MB
Format:
Adobe Portable Document Format
Description:
Collections