Evaluating the Effects of Subchronic Oxytocin Administration on Social Behaviors in Juvenile Mice

dc.contributor.author Berry, Kaitlyn
dc.date.accessioned 2020-06-08T15:21:58Z
dc.date.available 2020-06-08T15:21:58Z
dc.date.issued 2020-05-06
dc.description.abstract Previous research has demonstrated the importance of social interactions in typical development and growth. Recent research demonstrates oxytocin’s role in prosocial behaviors, and oxytocin has been proposed as a pharmacological treatment for certain social deficits. The purpose of this study is to explore the effects of sub-chronic oxytocin administration on social behaviors in male and female, juvenile mice. Mice underwent housing and drug manipulations to test the effects of sub-chronic oxytocin administration, isolation housing, and sex on social behaviors evaluated using a three chamber assay developed for determining sociability and the preference for social novelty. Results indicate sub-chronic oxytocin administration induces sex-specific changes in social behavior with an interaction between housing condition, drug treatment, and sex. These results suggest that there is a complex relationship existing between these variables that should be considered further in the prescription and use of oxytocin to treat social symptoms in clinical populations. en_US
dc.identifier.uri https://jewlscholar.mtsu.edu/handle/mtsu/6225
dc.language.iso en_US en_US
dc.publisher University Honors College Middle Tennessee State University en_US
dc.subject Behavioral and Health Sciences en_US
dc.subject oxytocin en_US
dc.subject mice social en_US
dc.subject juvenile en_US
dc.subject three chamber en_US
dc.title Evaluating the Effects of Subchronic Oxytocin Administration on Social Behaviors in Juvenile Mice en_US
dc.type Thesis en_US
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