Direct laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patient

dc.contributorMiddle Tennessee State University. Physics and Astronomy Department.en_US
dc.contributor.authorPellizzaro, Alineen_US
dc.contributor.authorWelker, Gabrielen_US
dc.contributor.authorScott, Daviden_US
dc.contributor.authorSolomon, Ranceen_US
dc.contributor.authorCooper, Jamesen_US
dc.contributor.authorFarone, Anthonyen_US
dc.contributor.authorFarone, Maryen_US
dc.contributor.authorMushi, Robert S.en_US
dc.contributor.authorAguinaga, Maria del Pilaren_US
dc.contributor.authorErenso, Danielen_US
dc.date.accessioned2014-06-24T15:41:58Z
dc.date.available2014-06-24T15:41:58Z
dc.date.issued2012-08-16en_US
dc.description.abstractUsing a laser trap, we have studied the properties of erythrocytes from a sickle cell anemia patient (SCA) after receiving an intravenous blood transfusion, and a normal adult individual carrying normal adult hemoglobin. The hemoglobin type and quantitation assessment was carried out by high performance liquid chromatography (HPLC). We conducted an analysis of the size distributions of the cells. By targeting those erythrocytes in the overlapping regions of size distributions, we have investigated their properties when the cells are trapped and released. The efficacy of the transfusion treatment is also studied by comparing the relative changes in deformation and the relaxation-time of the cells in the two samples.en_US
dc.identifier.citationBiomedical Optics Express. 2012 Aug 16;3(9):2190en_US
dc.identifier.urihttp://jewlscholar.mtsu.edu/handle/mtsu/4241
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.subjectExperimental physicsen_US
dc.subjectBiology and medicineen_US
dc.subjectOptical confinement and manipulationen_US
dc.subjectOptical tweezers or optical manipulationen_US
dc.titleDirect laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patienten_US
dc.typeResearch Articleen_US

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