Direct laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patient
Direct laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patient
dc.contributor | Middle Tennessee State University. Physics and Astronomy Department. | en_US |
dc.contributor.author | Pellizzaro, Aline | en_US |
dc.contributor.author | Welker, Gabriel | en_US |
dc.contributor.author | Scott, David | en_US |
dc.contributor.author | Solomon, Rance | en_US |
dc.contributor.author | Cooper, James | en_US |
dc.contributor.author | Farone, Anthony | en_US |
dc.contributor.author | Farone, Mary | en_US |
dc.contributor.author | Mushi, Robert S. | en_US |
dc.contributor.author | Aguinaga, Maria del Pilar | en_US |
dc.contributor.author | Erenso, Daniel | en_US |
dc.date.accessioned | 2014-06-24T15:41:58Z | |
dc.date.available | 2014-06-24T15:41:58Z | |
dc.date.issued | 2012-08-16 | en_US |
dc.description.abstract | Using a laser trap, we have studied the properties of erythrocytes from a sickle cell anemia patient (SCA) after receiving an intravenous blood transfusion, and a normal adult individual carrying normal adult hemoglobin. The hemoglobin type and quantitation assessment was carried out by high performance liquid chromatography (HPLC). We conducted an analysis of the size distributions of the cells. By targeting those erythrocytes in the overlapping regions of size distributions, we have investigated their properties when the cells are trapped and released. The efficacy of the transfusion treatment is also studied by comparing the relative changes in deformation and the relaxation-time of the cells in the two samples. | en_US |
dc.identifier.citation | Biomedical Optics Express. 2012 Aug 16;3(9):2190 | en_US |
dc.identifier.uri | http://jewlscholar.mtsu.edu/handle/mtsu/4241 | |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_US |
dc.subject | Experimental physics | en_US |
dc.subject | Biology and medicine | en_US |
dc.subject | Optical confinement and manipulation | en_US |
dc.subject | Optical tweezers or optical manipulation | en_US |
dc.title | Direct laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patient | en_US |
dc.type | Research Article | en_US |
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